Suicidal ideation during treatment of depression with escitalopram and nortriptyline in Genome-Based Therapeutic Drugs for Depression (GENDEP): a clinical trial

@article{Perroud2009SuicidalID,
  title={Suicidal ideation during treatment of depression with escitalopram and nortriptyline in Genome-Based Therapeutic Drugs for Depression (GENDEP): a clinical trial},
  author={N. Perroud and R. Uher and A. Maru{\vs}i{\vc} and M. Rietschel and O. Mors and N. Henigsberg and J. Hauser and W. Maier and D. Souery and A. Placentino and A. Szczepankiewicz and Lisbeth J{\o}rgensen and J. Strohmaier and A. Zobel and C. Giovannini and A. Elkin and C. Gunasinghe and J. Gray and D. Campbell and B. Gupta and A. Farmer and P. McGuffin and K. Aitchison},
  journal={BMC Medicine},
  year={2009},
  volume={7},
  pages={60 - 60}
}
BackgroundSuicidal thoughts and behaviours during antidepressant treatment, especially during the first weeks of treatment, have prompted warnings by regulatory bodies. The aim of the present study is to investigate the course and predictors of emergence and worsening of suicidal ideation during tricyclic antidepressant and serotonin reuptake inhibitor treatment.MethodsIn a multicentre part-randomised open-label study, 811 adult patients with moderate to severe unipolar depression were… Expand
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