SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling in Pseudomonas aeruginosa.

@article{Shi2015SuhBIA,
  title={SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling in Pseudomonas aeruginosa.},
  author={Jing Shi and Yongxin Jin and Ting Bian and Kewei Li and Ziyu Sun and Zhihui Cheng and Shouguang Jin and Weihui Wu},
  journal={Molecular microbiology},
  year={2015},
  volume={98 2},
  pages={370-83}
}
Translation elongation is modulated by various ribosome-binding proteins. Environmental stresses, such as starvation and antibiotics, can cause stalling of bacterial ribosomes, which may alter gene expression through a transcription or translation attenuation mechanism. In Pseudomonas aeruginosa, the expression of MexXY multidrug efflux system, which plays a significant role in resistance against aminoglycoside antibiotics, is controlled by a translation surveillance mechanism. Stalling of… CONTINUE READING
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