Sugar glues for broken neurons.

  title={Sugar glues for broken neurons.},
  author={Vimal Paritosh Swarup and Caitlin P Mencio and Vladimir Hlady and Balagurunathan Kuberan},
  journal={Biomolecular concepts},
  volume={4 3},
Proteoglycans (PGs) regulate diverse functions in the central nervous system (CNS) by interacting with a number of growth factors, matrix proteins, and cell surface molecules. Heparan sulfate (HS) and chondroitin sulfate (CS) are two major glycosaminoglycans present in the PGs of the CNS. The functionality of these PGs is to a large extent dictated by the fine sulfation patterns present on their glycosaminoglycan (GAG) chains. In the past 15 years, there has been a significant expansion in our… CONTINUE READING