Sugar-dependent photodynamic effect of glycoconjugated porphyrins: a study on photocytotoxicity, photophysical properties and binding behavior to bovine serum albumin (BSA).

@article{Obata2007SugardependentPE,
  title={Sugar-dependent photodynamic effect of glycoconjugated porphyrins: a study on photocytotoxicity, photophysical properties and binding behavior to bovine serum albumin (BSA).},
  author={M. Obata and S. Hirohara and Kohei Sharyo and Hiroki Alitomo and K. Kajiwara and S. Ogata and M. Tanihara and C. Ohtsuki and S. Yano},
  journal={Biochimica et biophysica acta},
  year={2007},
  volume={1770 8},
  pages={
          1204-11
        }
}
The photocytotoxicity of four glycoconjugated porphyrins, namely 5,10,15,20-tetrakis[4-(beta-D-glucopyranosyloxy)phenyl]porphyrin (p-1a), 5,10,15,20-tetrakis[4-(beta-D-galactopyranosyloxy)phenyl]porphyrin (p-1b), 5,10,15,20-tetrakis[4-(beta-D-xylopyranosyloxy)phenyl]porphyrin (p-1c) and 5,10,15,20-tetrakis[4-(beta-D-arabinopyranosyloxy)phenyl]porphyrin (p-1d), was evaluated in HeLa cells in the concentration range from 1 to 7 microM using a light dose of 16 J x cm(-2) with a wavelength greater… Expand
Synthesis, photophysical properties and sugar-dependent in vitro photocytotoxicity of pyrrolidine-fused chlorins bearing S-glycosides.
Structure-photodynamic effect relationships of 24 glycoconjugated photosensitizers in HeLa cells.
Small change in structure leads to large difference in protein photocleavage: two porphyrins bearing rhodanine-based pendants.
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Modulation of porphyrin binding to serum albumin by pH.
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