Sugammadex and neostigmine dose-finding study for reversal of shallow residual neuromuscular block.

@article{Schaller2010SugammadexAN,
  title={Sugammadex and neostigmine dose-finding study for reversal of shallow residual neuromuscular block.},
  author={Stefan J Schaller and Heidrun Fink and K. Ulm and Manfred Blobner},
  journal={Anesthesiology},
  year={2010},
  volume={113 5},
  pages={1054-60}
}
INTRODUCTION Sugammadex effectively and rapidly reverses deep to moderate rocuronium-induced neuromuscular block. However, the required dose of sugammadex for smaller degrees of residual block is unknown. Therefore we investigated the efficacy of sugammadex and neostigmine at a train-of-four (TOF) ratio of 0.5. METHODS After ethics committee (Munich, Germany) approval and written informed consent were obtained, 99 patients were anesthetized with propofol, remifentanil, and rocuronium… CONTINUE READING
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