Sugammadex: a cyclodextrin to reverse neuromuscular blockade in anaesthesia.

  title={Sugammadex: a cyclodextrin to reverse neuromuscular blockade in anaesthesia.},
  author={F. Marchesi Donati},
  journal={Expert opinion on pharmacotherapy},
  volume={9 8},
BACKGROUND Neuromuscular blocking agents are used to provide relaxation and immobility during surgery. To avoid residual paralysis after anaesthesia, reversal of blockade is commonly accomplished with anticholinesterase agents but these drugs have cardiovascular side effects and incomplete effectiveness. Sugammadex is a cyclodextrin that binds rocuronium and chemically similar neuromuscular blocking drugs. OBJECTIVE Published data on the effectiveness of sugammadex as a reversal agent were… CONTINUE READING

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