Sudden death caused by pulmonary thromboembolism in Proteus syndrome.

@article{Slavotinek2000SuddenDC,
  title={Sudden death caused by pulmonary thromboembolism in Proteus syndrome.},
  author={Anne M Slavotinek and Scott J Vacha and Kathryn F. Peters and Leslie G. Biesecker},
  journal={Clinical genetics},
  year={2000},
  volume={58 5},
  pages={386-9}
}
We report 3 patients with Proteus syndrome (PS) who died suddenly from pulmonary embolism (PE). The first patient was a male diagnosed with PS at 12 years who had varicose veins, portal vein thrombosis, right iliac vein occlusion and recurrent PE. At age 25 years, he was admitted to the hospital with a severe headache. Despite therapeutic doses of warfarin, investigations for an acute episode of breathlessness showed PE and he was unable to be resuscitated. The second case was a 9-year-old male… CONTINUE READING