Sudden cardiac death from acute fluoride intoxication: the role of potassium.

@article{McIvor1987SuddenCD,
  title={Sudden cardiac death from acute fluoride intoxication: the role of potassium.},
  author={Michael E. McIvor and Curtis E Cummings and Morton M. Mower and Robert E Wenk and J A Lustgarten and Ramon Baltazar and J{\'e}r{\^o}me Salomon},
  journal={Annals of emergency medicine},
  year={1987},
  volume={16 7},
  pages={777-81}
}
The mechanism of sudden cardiac death following acute fluoride intoxication has been thought to result from profound hypocalcemia produced by the precipitation of calcium fluoride salts. In studies of a canine model, the onset of lethal ventricular arrhythmias was temporally more associated with an elevation of serum potassium than with a drop in serum calcium. Fluoride-induced hyperkalemia could not be prevented with glucose, insulin, or bicarbonate. In the erythrocytes, a five-minute exposure… CONTINUE READING

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