Sudan I induces genotoxic effects and oxidative DNA damage in HepG2 cells.

@article{An2007SudanII,
  title={Sudan I induces genotoxic effects and oxidative DNA damage in HepG2 cells.},
  author={Yu An and Liping Jiang and Jun Cao and Chengyan Geng and Laifu Zhong},
  journal={Mutation research},
  year={2007},
  volume={627 2},
  pages={164-70}
}
Sudan I, a synthetic lipid soluble azo pigment, is widely used in various industrial fields. However, Sudan I has not been approved at any level of food production, since there are many inconclusive reports relating to its genotoxicity and carcinogenicity in humans. The aim of this study was to assess the genotoxic effects of Sudan I and to identify and clarify the reaction mechanisms by use of human hepatoma HepG2 cells. To study the genotoxic effects of Sudan I, the comet assay and… CONTINUE READING
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