Sucrose ingestion causes opioid analgesia.

@article{Segato1997SucroseIC,
  title={Sucrose ingestion causes opioid analgesia.},
  author={Fernando Segato and C Castro-Souza and E. N. Segato and Silvio Morato and N. C. Coimbra},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={1997},
  volume={30 8},
  pages={981-4}
}
The intake of saccharin solutions for relatively long periods of time causes analgesia in rats, as measured in the hot-plate test, an experimental procedure involving supraspinal components. In order to investigate the effects of sweet substance intake on pain modulation using a different model, male albino Wistar rats weighing 180-200 g received either tap water or sucrose solutions (250 g/l) for 1 day or 14 days as their only source of liquid. Each rat consumed an average of 15.6 g sucrose… CONTINUE READING

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