Sucrose formulated recombinant human antihemophilic factor VIII is safe and efficacious for treatment of hemophilia A in home therapy--International Kogenate-FS Study Group.

@article{Abshire2000SucroseFR,
  title={Sucrose formulated recombinant human antihemophilic factor VIII is safe and efficacious for treatment of hemophilia A in home therapy--International Kogenate-FS Study Group.},
  author={Thomas C. Abshire and H H Brackmann and Inge Scharrer and Keith Hoots and Claire Gazengel and Jerry S. Powell and Eduard Gorina and Elke Kellermann and Evan Vosburgh},
  journal={Thrombosis and haemostasis},
  year={2000},
  volume={83 6},
  pages={811-6}
}
To add an increased level of safety to antihemophilic factor replacement therapy, a full-length, recombinant Factor VIII (rFVIII) product has been developed without human-derived plasma proteins during purification and formulation and using an additional solvent/detergent viral inactivation step. This first clinical trial of a sucrose-formulated full-length… CONTINUE READING