Sucrose: a novel permeability marker for gastroduodenal disease.

  title={Sucrose: a novel permeability marker for gastroduodenal disease.},
  author={Jon B. Meddings and Lloyd R. Sutherland and N I Byles and John L Wallace},
  volume={104 6},
BACKGROUND Nonsteroidal anti-inflammatory agents (NSAIDs) commonly cause asymptomatic gastroduodenal damage that may be clinically severe. At present the only method to determine the presence or absence of such damage is by invasive techniques such as endoscopy. Because distal small intestinal damage can be noninvasively detected with oral permeability tests, the hypothesis that gastroduodenal damage could be detected using similar methods was examined in the present study. RESULTS Animal… CONTINUE READING