Sucrase-isomaltase: a marker of foetal and malignant epithelial cells of the human colon.

@article{Zweibaum1983SucraseisomaltaseAM,
  title={Sucrase-isomaltase: a marker of foetal and malignant epithelial cells of the human colon.},
  author={Alain Zweibaum and Nicole Triadou and Mich{\`e}le Kedinger and Chantal Augeron and S Robine-L{\'e}on and Martha L. Pinto and Monique Rousset and Katy Haffen},
  journal={International journal of cancer},
  year={1983},
  volume={32 4},
  pages={407-12}
}
The presence of sucrase-isomaltase (SI), a glycoprotein hydrolase normally restricted to the brush border membrane of the enterocytes of the small intestine, was investigated in tumours which developed in nude mice inoculated with six human colon carcinoma cell lines (HT-29, Caco-2, HRT-18, HCT-8R, SW-480, and CO-115). Foetal and normal adult human small intestines and colons were used as controls. SI was studied by (1) immunofluorescence with rabbit antibodies raised against purified human… CONTINUE READING