Succinylcholine pretreatment using gallamine or mivacurium during rapid sequence induction in children: a randomized, controlled study.

@article{Theroux2001SuccinylcholinePU,
  title={Succinylcholine pretreatment using gallamine or mivacurium during rapid sequence induction in children: a randomized, controlled study.},
  author={Mary C. Theroux and John B. Rose and S Iyengar and Michael S. Katz},
  journal={Journal of clinical anesthesia},
  year={2001},
  volume={13 4},
  pages={
          287-92
        }
}
Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia
TLDR
Pretreatment with rocuronium prevents the rise in serum potassium induced by succinylcholine, and this effect is limited to patients who presented for elective general surgical procedures.
The comparison of atracurium and lidocaine for decreasing succinylcholine induced fasciculation, myalgia and serum potassium change in patients during induction of anesthesia
TLDR
Lidocaine is more effective than atracurium in decreasing the occurrence and severity of myalgia, following succinylcholine injection at induction of anesthesia in patients at risk of aspiration.
Pretreatment with remifentanil is associated with less succinylcholine-induced fasciculation.
TLDR
It is indicated that remifentanil can reduce the duration and the intensity of succinylcholine induced fasciculation, however, it induces greater bradycardia.
Prevention of Succinylcholine-induced Fasciculation and Myalgia: A Meta-analysis of Randomized Trials
TLDR
Myalgia may best be prevented with muscle relaxants, lidocaine, or nonsteroidal antiinflammatory drugs, and data that allow for a risk–benefit assessment are lacking for other drugs.
Effects of rocuronium pretreatment on muscle enzyme levels following succinylcholine.
TLDR
Precurarization with rocuronium was effective in reducing the succinylcholine-induced rise in creatinine kinase, biochemically manifested as rise in CK.
Consequences of Succinylcholine Administration to Patients Using Statins
TLDR
The study results suggest that the effect of succinylcholine given to patients taking statins is likely to be small and probably of limited clinical consequence, although the difference seems unlikely to be clinically important.
Neuromuscular Effects of Rocuronium Bromide in Patients in Statin Therapy for at least Three Months
TLDR
The onset time of rocuronium decreases and its duration time increases in patients in long‐term statin therapy and there were no significant differences in the basic clinical characteristics between the two groups.
PREVENTION OF SUCCINYLCHOLINE INDUCED MUSCULAR EFFECTS BY PRETREATMENT WITH ROCURONIUM
We have studied in 60 patients undergoing minor muscle cutting surgeries under general anesthesia, the effectiveness and sequelae of pretreatment with rocuronium for reducing muscular side effects
The place of suxamethonium in pediatric anesthesia
TLDR
The arguments for and against suxamethonium are set out below by two international experts, Marcin Rawicz from Poland and Barbara Brandom from USA, to allow the reader an objective evaluation with which to make an informed choice about the use of the drug in their practice.
Controversies in rapid sequence intubation in children
TLDR
Though more research is needed, the available data allow for the development of protocols that will result in a rational, scenario-based approach to rapid sequence intubation in children.
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References

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Rocuronium versus succinylcholine : Are they equally effective during rapid-sequence induction of anesthesia?
TLDR
It is concluded that rocuronium is a reasonable substitute for succinylcholine in children for rapid-sequence intubation when a rapid return to spontaneous respiration is not desired.
Comparison of intubating conditions after rapacuronium (Org 9487) and succinylcholine following rapid sequence induction in adult patients.
TLDR
After rapid sequence induction of anaesthesia in adults, clinically acceptable intubating conditions were achieved less frequently after rapacuronium 1.5 mg kg-1 than after succinylcholine.
Rocuronium prevents succinylcholine-induced fasciculations
TLDR
The incidence and severity of succinylcholine fasciculations can be reduced by giving 0.05 mg·kg−1 rocuronium either 1.5 min or 3 min before succinylchantoline, as well as the onset of paralysis and duration of blockade.
Neuromuscular and cardiovascular effects of mivacurium in children.
TLDR
The neuromuscular and cardiovascular effects of mivacurium chloride (BW B1090U) were evaluated in 90 children (2-12 yr) during N2O:O2 halothane or N2 o2 narcotic anesthesia to determine dose response relationships under the different anesthetic regimens.
Changes in Serum Potassium after Suxamethonium in Children
TLDR
Individual children in each group had significant increases in serum potassium, but this phenomenon was less common than has been reported in adults and changes could not be related to the presence or degree of muscular fasciculations.
Dose‐Response of Rocuronium Bromide in Children Anesthetized with Propofol: A Comparison with Succinylcholine
TLDR
The present dose‐response data support the use of rocuronium at a dose of 1.2 mg/kg when rapid onset and intermediate‐duration neuro‐muscular block are needed in children.
The Clinical Neuromuscular Pharmacology of Mivacurium Chloride (BW B1090U). A Short‐acting Nondepolarizing Ester Neuromuscular Blocking Drug
TLDR
Mivacurium may offer increased versatility in providing clinical muscle relaxation in a variety of situations, and further studies seem appropriate.
Oral diazepam premedication reduces the incidence of post-succinylcholine muscle pains
  • A. Davies
  • Medicine
    Canadian Anaesthetists' Society journal
  • 1983
TLDR
Diazepam and control groups did not differ significantly in extent of fasciculations or ease of intubation, However, only 15 per cent of the diazepam premedicated patients had myalgias postoperatively compared to 50 per centof the control patients, a statistically significant difference (p = 0.04).
Relation of precurarization to suxamethonium to provide ease of intubation and to prevent post-suxamethonium muscle pains
  • J. Wig, I. Bali
  • Medicine
    Canadian Anaesthetists' Society journal
  • 1979
TLDR
It is shown that tubocurarine 0.07 mg-kg-1 and suxamethonium 2 mg- kg-1 was the ideal combination with the best intubation conditions and the lowest incidence of post-suxamETHonium muscle pains, and gallamine 0.1 and 0.2 mg-km3 were satisfactory, although less efficient than the combination with either tubourarine or gallamine.
Biochemical changes following suxamethonium
TLDR
Forty patients were investigated for serum myoglobin changes following induction of anaesthesia but before the commencement of surgery to reduce the fasciculations.
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