Succinylcholine-induced hyperkalemia in the rat following radiation injury to muscle.

@article{Cairoli1982SuccinylcholineinducedHI,
  title={Succinylcholine-induced hyperkalemia in the rat following radiation injury to muscle.},
  author={V J Cairoli and Anthony D. Ivankovich and D Vucicevic and K R Patel},
  journal={Anesthesia and analgesia},
  year={1982},
  volume={61 2},
  pages={83-6}
}
During anesthetic preparation of a patient who had received routine radiation therapy for sarcoma of the leg, cardiac collapse occurred following succinylcholine (SCh) administration. Experiments were designed to test the hypothesis that radiation injury to muscle might cause increased sensitivity to SCh similar to that reported in patients with muscle trauma, severe burns, and lesions causing muscle denervation. Venous plasma potassium levels and arterial blood gas tensions were measured in… CONTINUE READING