Succinate dehydrogenase B gene mutations predict survival in patients with malignant pheochromocytomas or paragangliomas.

@article{Amar2007SuccinateDB,
  title={Succinate dehydrogenase B gene mutations predict survival in patients with malignant pheochromocytomas or paragangliomas.},
  author={Laurence Amar and Eric Baudin and Nelly Burnichon and S{\'e}verine Peyrard and Stephane S Silvera and J{\'e}r{\^o}me Bertherat and Xavier Y Bertagna and Martin Schlumberger and Xavier Jeunema{\^i}tre and Anne-paule Gimenez-Roqueplo and P. -F. Plouin},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2007},
  volume={92 10},
  pages={3822-8}
}
CONTEXT Pheochromocytomas and paragangliomas may be malignant either at presentation or during recurrence, but the clinical course of malignant tumors is unpredictable. OBJECTIVE The objective was to analyze survival according to clinical characteristics at diagnosis of malignancy and the presence or absence of SDHB mutations. DESIGN This was a retrospective cohort study. SETTING AND PARTICIPANTS A total of 54 patients with malignant tumors were included. Malignancy was scored according… CONTINUE READING
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