Succinate dehydrogenase - Assembly, regulation and role in human disease.

  title={Succinate dehydrogenase - Assembly, regulation and role in human disease.},
  author={Jared Rutter and Dennis R Winge and Joshua D Schiffman},
  volume={10 4},
Succinate dehydrogenase (or Electron Transport Chain Complex II) has been the subject of a focused but significant renaissance. This complex, which has been the least studied of the mitochondrial respiratory complexes has seen renewed interest due to the discovery of its role in human disease. Under this heightened scrutiny, the succinate dehydrogenase complex has proven to be a fascinating machine, whose regulation and assembly requires additional factors that are beginning to be discovered… CONTINUE READING

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