Successive contractile periods activate mitochondria at the onset of contractions in intact rat cardiac trabeculae.

@article{Wst2018SuccessiveCP,
  title={Successive contractile periods activate mitochondria at the onset of contractions in intact rat cardiac trabeculae.},
  author={Rob C I W{\"u}st and Ger J M Stienen},
  journal={Journal of applied physiology},
  year={2018},
  volume={124 4},
  pages={1003-1011}
}
The rate of oxidative phosphorylation depends on the contractile activity of the heart. Cardiac mitochondrial oxidative phosphorylation is determined by free ADP concentration, mitochondrial Ca2+ accumulation, mitochondrial enzyme activities, and Krebs cycle intermediates. The purpose of the present study was to examine the factors that limit oxidative… CONTINUE READING