Successful uses of magnesium sulfate for torsades de pointes in children with long QT syndrome

  title={Successful uses of magnesium sulfate for torsades de pointes in children with long QT syndrome},
  author={Kenji Hoshino and Kiyoshi Ogawa and Takashi Hishitani and Takeshi Isobe and Yoshikatsu Etoh},
  journal={Pediatrics International},
Background: Administration of magnesium sulfate (MgSO4) is an effective and safe treatment for torsades de pointes (TdP) associated with acquired long QT syndrome (LQTS) in adults. As for children, there are few reports focusing on it. The authors discuss the efficacy of MgSO4 for TdP in children with congenital and acquired LQTS. The authors also discuss the optimal administration dosage and serum magnesium (SMg) concentration during MgSO4 therapy. 
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  • W. Baker
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    European heart journal. Cardiovascular pharmacotherapy
  • 2017
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Magnesium therapy for torsades de pointes.
Treatment of torsade de pointes with magnesium sulfate.
MgSO4 is a very effective and safe treatment for TdP, and its use is therefore recommended as the first line of therapy for TDP.
Torsade de pointes and long QT syndrome following major blood transfusion
Treatment with a magnesium infusion restored the QT interval to normal and temporary ventricular pacing prevented further ventricular arrhythmias in a patient with acquired long QT syndrome following transfusion of a large volume of blood.
Right ventricular monophasic action potentials in patients with long QT syndrome.
In 3 patients with the long QT syndrome, one caused by quinidine and 2 of congenital origin, right ventricular monophasic action potentials were excessively prolonged and of varying shapes in