Successful uses of magnesium sulfate for torsades de pointes in children with long QT syndrome
@article{Hoshino2006SuccessfulUO, title={Successful uses of magnesium sulfate for torsades de pointes in children with long QT syndrome}, author={Kenji Hoshino and Kiyoshi Ogawa and Takashi Hishitani and Takeshi Isobe and Yoshikatsu Etoh}, journal={Pediatrics International}, year={2006}, volume={48} }
Background: Administration of magnesium sulfate (MgSO4) is an effective and safe treatment for torsades de pointes (TdP) associated with acquired long QT syndrome (LQTS) in adults. As for children, there are few reports focusing on it. The authors discuss the efficacy of MgSO4 for TdP in children with congenital and acquired LQTS. The authors also discuss the optimal administration dosage and serum magnesium (SMg) concentration during MgSO4 therapy.
34 Citations
Termination of drug-induced torsades de pointes with overdrive pacing.
- MedicineThe American journal of emergency medicine
- 2010
Long QT syndrome: A therapeutic challenge
- Medicine, BiologyAnnals of pediatric cardiology
- 2008
An impressive genotype-phenotype correlation has been noted and genotype identification has enabled genotype specific therapies and Beta blockers continue to be the primary treatment for prevention of life threatening arrhythmias in the majority of patients.
Pediatric cardiology emergencies - the role of Long QT Syndrome among arrhythmias
- MedicineEuropean Journal of Translational and Clinical Medicine
- 2019
It is aimed to show that a very important part of treatment is not only pharmacotherapy, especially beta-blockers, but change of lifestyle plays a significant role in the management of families with LQTS.
Anesthesia for children with long QT syndrome: Challenges and solutions from pediatric studies
- Medicine
- 2017
Assessment of corrected QT interval in sickle cell disease patients who undergo erythroapheresis
- Medicine, BiologyTransfusion medicine
- 2007
Extension of the QT interval is characterized by syncope and cardiac arrest and often occurs in association with medical therapies and procedures and in patients with sickle cell disease.
Pediatric Tachyarrhythmias: Diagnosis and Management
- MedicineCurrent Pediatrics Reports
- 2017
This review discusses the mechanism, presentation, and management of pediatric tachyarrhythmias, which focuses on SVT, as it is the most common cardiac arrhythmia in children requiring intervention, but also discusses other life-threatening arrh rhythmias including ventricular arrhythmia and Wolff-Parkinson-White syndrome.
Anthracyclines for acute lymphoblastic leukemia in a child with congenital long QT syndrome
- MedicineInternational journal of hematology
- 2011
A child with ALL complicated by congenital LQTS who was treated with anthracyclines caused QT-interval prolongation, but this was uneventful with the concomitant administration of magnesium sulfate.
Efficacy and Safety of a Ketogenic Diet in Children and Adolescents with Refractory Epilepsy—A Review
- MedicineNutrients
- 2020
It is imperative to study and understand the metabolic profiles of patients with epilepsy in order to isolate which dietary restrictions are necessary to maximize clinical benefit.
Treating arrhythmias with adjunctive magnesium: identifying future research directions
- Biology, MedicineEuropean heart journal. Cardiovascular pharmacotherapy
- 2017
A number of limitations and gaps to the literature exist, including an unclear link between correction of intracellular magnesium concentrations and both mechanistic and clinical outcomes, small sample sizes, varying routes of administration and doses, as well as short follow-up periods are highlighted.
Magnesium in man: implications for health and disease.
- Biology, MedicinePhysiological reviews
- 2015
An extensive and comprehensive overview of Mg(2+) research over the last few decades is provided, focusing on the regulation of M g(2+) homeostasis in the intestine, kidney, and bone and disturbances which may result in hypomagnesemia.
References
SHOWING 1-10 OF 42 REFERENCES
Magnesium sulfate therapy for sustained monomorphic ventricular tachycardia.
- MedicineThe American journal of cardiology
- 1989
Treatment of torsade de pointes with magnesium sulfate.
- MedicineCirculation
- 1988
MgSO4 is a very effective and safe treatment for TdP, and its use is therefore recommended as the first line of therapy for TDP.
Torsade de pointes and long QT syndrome following major blood transfusion
- MedicineAnaesthesia
- 1992
Treatment with a magnesium infusion restored the QT interval to normal and temporary ventricular pacing prevented further ventricular arrhythmias in a patient with acquired long QT syndrome following transfusion of a large volume of blood.
Effects of magnesium sulfate on cardiac conduction and refractoriness in humans.
- MedicineJournal of the American College of Cardiology
- 1986
Electrophysiologic effects of intravenous magnesium in patients with normal conduction systems and no clinical evidence of significant cardiac disease.
- MedicineAmerican heart journal
- 1988
Effect of the infusion of magnesium sulfate during atrial pacing on ECG intervals, serum electrolytes, and blood pressure.
- MedicineAmerican heart journal
- 1989
Effects of intravenous magnesium sulfate on arrhythmias in patients with congestive heart failure.
- Medicine, BiologyAmerican heart journal
- 1993
Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2)
- Medicine, BiologyThe Lancet
- 1992
Right ventricular monophasic action potentials in patients with long QT syndrome.
- MedicineBritish heart journal
- 1978
In 3 patients with the long QT syndrome, one caused by quinidine and 2 of congenital origin, right ventricular monophasic action potentials were excessively prolonged and of varying shapes in…