Successful use of the excimer laser for generalized psoriasis in an ustekinumab non-responder.

@article{Malakouti2014SuccessfulUO,
  title={Successful use of the excimer laser for generalized psoriasis in an ustekinumab non-responder.},
  author={Mona Malakouti and Gabrielle Brown and Eric Sorenson and Argentina Leon and John Koo and Ethan Charles Levin},
  journal={Dermatology online journal},
  year={2014},
  volume={21 3}
}
Effective treatments for moderate to severe psoriasis are phototherapy and biologics. These treatments are similar in that they both decrease cutaneous immune system hyperactivity yet do so via different mechanisms. Our patient, a 63 year old Asian male had a rapid response to treatment with the high dose excimer laser, having previously failed treatment with 28 weeks of ustekinumab therapy. A pre-treatment biopsy of a psoriatic plaque was found to contain relatively low levels of IFN-γ (Th1… CONTINUE READING

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