Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia.

@article{Almond2006SuccessfulUO,
  title={Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia.},
  author={Christopher S D Almond and James Harrington and Ravi R Thiagarajan and Christine N. Duncan and R A Lapierre and David R. Halwick and Elizabeth D. Blume and Pedro J. del Nido and Ellis J. Neufeld and Francis X. McGowan},
  journal={The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation},
  year={2006},
  volume={25 11},
  pages={1376-9}
}
Bivalirudin, a direct thrombin inhibitor, has recently emerged as a promising option for anti-coagulation during cardiopulmonary bypass in patients who cannot receive heparin. There is limited experience with the use of bivalirudin in children. We present the case of a child with heparin-induced thrombocytopenia with thrombosis (HIT Type II) who underwent successful orthotopic cardiac transplantation using bivalirudin as the primary anti-coagulant for cardiopulmonary bypass. 

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