Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest.

@article{Rosenblatt2006SuccessfulUO,
  title={Successful use of a 20\% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest.},
  author={Meg Rosenblatt and Mark Abel and Gregory W. Fischer and Chad J Itzkovich and James B. Eisenkraft},
  journal={Anesthesiology},
  year={2006},
  volume={105 1},
  pages={
          217-8
        }
}
The patient was a 58-yr-old, 82-kg, 170-cm male who presented for arthroscopic repair of a torn rotator cuff in the right shoulder. His medical history was significant for coronary artery bypass graft surgery at age 43 yr. He gave a history of angina upon exertion and occasionally at rest. He declined further preoperative cardiac workup but was considered by his cardiologist to be stable on medical therapy. This included nitroglycerine as needed, lisinopril, atenolol isosorbide mononitrate, and… Expand

Paper Mentions

Interventional Clinical Trial
The aim of this study is to investigate whether intravenous lipid emulsion is effective in attenuating the clinical effects of a cardioactive drug, exemplified by the beta-blocking… Expand
ConditionsBlood Pressure, Drug Overdose, Overdose of Beta-adrenergic Blocking Drug
InterventionDrug
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A case of bupivacaine systemic toxicity in which successful resuscitation may have been aided by the very early administration of lipid emulsion, in conjunction with effective CPR is presented, adding credence to the value of lipidEmulsion for rescue from local anesthetic systemic toxicity and also suggests the need for further study to determine the optimal timing of its administration. Expand
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