Successful treatment with a low-dose cisplatin–etoposide regimen for patients with diencephalic syndrome

@article{Sardi2012SuccessfulTW,
  title={Successful treatment with a low-dose cisplatin–etoposide regimen for patients with diencephalic syndrome},
  author={Iacopo Sardi and Cecilia Bresci and Elisabetta Schiavello and Veronica Biassoni and Valentina Fratoni and Stefania Cardellicchio and Lorenzo Genitori and M. Rita Aric{\`o} and Maura Massimino},
  journal={Journal of Neuro-Oncology},
  year={2012},
  volume={109},
  pages={375-383}
}
Diencephalic syndrome (DS) is a rare but rapidly fatal condition, usually occurring during the first year of life, as a result of a hypothalamic/chiasmatic tumor. The purpose of this study was to induce an objective tumor response and to achieve rapid weight recovery by using ten three-day courses of reduced-dose cisplatin–etoposide. Between 2004 and 2009, eight pediatric patients with DS as a result of an hypothalamic tumor and with a median age at diagnosis of 6.5 months (range 4–60 months… CONTINUE READING
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