Successful treatment of the idiopathic restless legs syndrome in a randomized double-blind trial of oxycodone versus placebo.

@article{Walters1993SuccessfulTO,
  title={Successful treatment of the idiopathic restless legs syndrome in a randomized double-blind trial of oxycodone versus placebo.},
  author={Arthur S. Walters and Mary L. Wagner and W. Hening and Kenneth W. Grasing and Richard Mills and Sudhansu Chokroverty and Neil Kavey},
  journal={Sleep},
  year={1993},
  volume={16 4},
  pages={
          327-32
        }
}
In a double-blind randomized crossover trial, oxycodone or placebo was given in divided night-time doses to 11 patients with idiopathic restless legs syndrome (RLS) for 2 weeks prior to appropriate polysomnographic studies. Under double-blinded conditions, patients were asked to do daily ratings of their leg sensations, motor restlessness and daytime alertness on a 1-4 scale for the 2 weeks prior to the polysomnographic studies and for the nights of the polysomnographic studies as well. Leg… 
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