Successful treatment of multidrug-resistant Acinetobacter baumannii ventriculitis with intravenous and intraventricular colistin.

@article{Dalgi2009SuccessfulTO,
  title={Successful treatment of multidrug-resistant Acinetobacter baumannii ventriculitis with intravenous and intraventricular colistin.},
  author={Nazan Dalgiç and Yemlihan Ceylan and Mesut Sancar and Leyla Telhan and Ihsan Kafadar and Halit Çavuşoğlu and Ozben Ceylan and Ozlem Hasim},
  journal={Annals of tropical paediatrics},
  year={2009},
  volume={29 2},
  pages={141-7}
}
Management of multidrug-resistant Acinetobacter baumannii (MDRAB) meningitis/ventriculitis is a difficult therapeutic problem owing to the limited penetration of antibiotics into cerebrospinal fluid (CSF). A 2-month-old girl with ventriculitis caused by MDRAB is reported. Despite therapy with intravenous (IV) colistin ventricular fluid, cultures remained positive for MDRAB. Institution of combination therapy with IV and intraventricular colistin resulted in a successful clinical and… CONTINUE READING