Successful treatment of localised radiation lesions in rats and humans by mesenchymal stem cell transplantation.

@article{Kotenko2012SuccessfulTO,
  title={Successful treatment of localised radiation lesions in rats and humans by mesenchymal stem cell transplantation.},
  author={Konstantin V. Kotenko and B. B. Moroz and N M Nadezhina and I A Galstyan and Ilya I Eremin and J Deshevoy and V. G. Lebedev and T S Slobodina and D Grinakovskaya and Yu. A. Zhgutov and Andrew Bushmanov},
  journal={Radiation protection dosimetry},
  year={2012},
  volume={151 4},
  pages={661-5}
}
Transplantation of mesenchymal stem cells (MSCs), at early and later stages after local exposure of rats to 140 Gy 90Sr/90Y beta radiation, was found to stimulate recovery of damaged skin. The area of local radiation injuries (LRIs) and accelerated healing of radiation ulcers was obtained. Clinical evolution showed the high efficiency of the transplantations of autologous MSCs for the treatment of deep beam ulcers, usually refractive to standard conservative treatment. Analogous to our results… CONTINUE READING