Successful treatment of intravenously abused oral Opana ER‐induced thrombotic microangiopathy without plasma exchange

@article{Miller2014SuccessfulTO,
  title={Successful treatment of intravenously abused oral Opana ER‐induced thrombotic microangiopathy without plasma exchange},
  author={Peter John Miller and Andrew Matthew Farland and Mary Ann Knovich and Katharine Batt and John R. Owen},
  journal={American Journal of Hematology},
  year={2014},
  volume={89}
}
In January 2013, the Centers for Disease Control and Prevention reported an illness associated with intravenous (IV) abuse of oral Opana ER (oxymorphone) in Tennessee. The clinical presentation of this syndrome was reported to resemble that of thrombotic thrombocytopenic purpura in the 15 patients reported; 12 were treated with plasma exchange. We report a similar case series of 15 patients with 18 episodes of thrombotic microangiopathy associated with recent IV abuse of oral Opana ER. In our… 

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