Successful treatment of experimental Escherichia coli infections in mice using phage: its general superiority over antibiotics.

@article{Smith1982SuccessfulTO,
  title={Successful treatment of experimental Escherichia coli infections in mice using phage: its general superiority over antibiotics.},
  author={H. Williams Smith and M. B. Huggins},
  journal={Journal of general microbiology},
  year={1982},
  volume={128 2},
  pages={307-18}
}
Anti-K 1 phages were more active in vitro and in vivo against an 018:K1:H7 ColV+ Escherichia coli strain, designated MW, than were other phages. A single intramuscular dose of one anti-K1 phage was more effective than multiple intramuscular does of tetracycline, ampicillin, chloramphenicol, or trimethoprim plus sulphafurazole in curing mice of a potentially lethal intramuscularly or intracerebrally induced infection of MW; it was at least as effective as multiple intramuscular doses of… CONTINUE READING
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