Successful treatment of cutaneous Langerhans cell histiocytosis with low‐dose methotrexate

@article{Steen2001SuccessfulTO,
  title={Successful treatment of cutaneous Langerhans cell histiocytosis with low‐dose methotrexate},
  author={A E Steen and Kay H. Steen and Ralf Bauer and Thomas Bieber},
  journal={British Journal of Dermatology},
  year={2001},
  volume={145}
}
Langerhans cell histiocytosis (LCH) can be a difficult therapeutic problem. We present a 40‐year‐old woman with a 4‐year history of LCH who was successfully treated with low‐dose methotrexate (20 mg weekly). 
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TLDR
Langerhans cell histiocytosis (LCH) is a rare disease, frequently affecting young children, and can be fatal in children under the age of five. Expand
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TLDR
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TLDR
A case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH), which is uncommon and usually other systems are affected. Expand
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TLDR
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Langerhans cell histiocytosis in the jugular foramen.
TLDR
The case of an adult patient with LCH affecting the jugular foramen is presented, and the relevant literature is reviewed. Expand
Successful treatment with cyclophosphamide of Langerhans cell histiocytosis involving the skin and lymph nodes in an adult patient
is a clear-cut demonstration of a differential expression pattern and subcellular localization of cell adhesion molecules, including strong N-cadherin expression and loss of b-catenin expression inExpand
[Langerhans cell histiocytosis].
TLDR
Three syndromes are actually the same pathogenic process: eosinophilic granuloma (single or multiple osseous localizations), Hand-Schüller-Christian disease (chronic form with bone and visceral dissemination) and Abt-Letterer-Siwe disease (disseminated and acute malignant presentation). Expand
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