Successful treatment of catecholaminergic polymorphic ventricular tachycardia with flecainide: a case report and review of the current literature.

@article{Pott2011SuccessfulTO,
  title={Successful treatment of catecholaminergic polymorphic ventricular tachycardia with flecainide: a case report and review of the current literature.},
  author={Christian Pott and Dirk G Dechering and Florian Reinke and Adam Muszyński and Stephan Zellerhoff and Alex Bittner and Julia K{\"o}be and Kristina Wasmer and Eric Schulze-Bahr and Gerold Moennig and Stefan Kotthoff and Lars Eckardt},
  journal={Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology},
  year={2011},
  volume={13 6},
  pages={897-901}
}
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmogenic disease that can cause sudden cardiac death due to ventricular fibrillation (VF). While pharmacological therapy with beta-blockers and/or Ca(2)(+) antagonists is often unreliable, a recent study has demonstrated that flecainide can effectively suppress arrhythmia in a murine model of CPVT as well as clinically in two human subjects suffering from CPVT. We here present the case of an 11-year-old boy… CONTINUE READING