Successful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus (SLE).

@article{Cela2010SuccessfulTO,
  title={Successful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus (SLE).},
  author={Iva Cela and Ira J. Miller and Robert Sanford Katz and Amy Rizman and Jamile M. Shammo},
  journal={Clinical advances in hematology & oncology : H&O},
  year={2010},
  volume={8 11},
  pages={
          806-9
        }
}
Systemic lupus erythematosus (SLE) is an inflammatory connective tissue disease mediated by a deregulated immune system and aberrant production of proinflammatory cytokines leading to multiorgan and tissue damage. Thrombocytopenia is a common complication in patients with SLE, with a prevalence that ranges from 7–30%.1-5 The 2 main mechanisms of thrombocytopenia in SLE are increased platelet destruction mediated by antiplatelet autoantibodies, similar to the mechanism seen in immune… CONTINUE READING

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Successful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus

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Successful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus ( SLE )

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