Successful treatment of acute chest syndrome with high-frequency oscillatory ventilation in pediatric patients.

@article{Wratney2004SuccessfulTO,
  title={Successful treatment of acute chest syndrome with high-frequency oscillatory ventilation in pediatric patients.},
  author={Angela T Wratney and Michael A. Gentile and Donna S Hamel and Ira M Cheifetz},
  journal={Respiratory care},
  year={2004},
  volume={49 3},
  pages={263-9}
}
Severe acute chest syndrome afflicts patients with sickle cell disease and can cause hypoxemia refractory to conventional treatments. Obstructive mucus plugging and the development of acute respiratory distress syndrome may underlie the pathophysiology of refractory hypoxemia in acute chest syndrome. Although high-frequency oscillatory ventilation (HFOV) is… CONTINUE READING