Successful treatment of CCL4-induced acute liver failure with portal vein arterialization in the rat.

@article{Nardo2006SuccessfulTO,
  title={Successful treatment of CCL4-induced acute liver failure with portal vein arterialization in the rat.},
  author={Bruno Nardo and Lorenza Puviani and Paolo Caraceni and Vincenzo Pacil{\`e} and Riccardo Bertelli and Paolo Beltempo and Giuseppe Cavallari and Pasquale Chieco and Milena Pariali and Anna Maria Pertosa and Graziella Angiolini and Marco Domenicali and Fabrizio Neri and Matvey Tsivian and Mauro Bernardi and Antonino Cavallari},
  journal={Transplantation proceedings},
  year={2006},
  volume={38 4},
  pages={1187-9}
}
INTRODUCTION Optimization of the conditions for regeneration of the native diseased liver is a major goal in patients with acute liver failure. This study sought to determine whether portal vein arterialization (PVA), which increases the oxygen supply to the liver, was protective in a rat model of liver failure. METHODS At 24 hours after CCl(4) intoxication, Sprague-Dawley rats (six per group) were assigned to receive PVA or as controls. We determined blood tests, histology, and 10-day… CONTINUE READING

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