Successful treatment by cyclooxyenase-2 inhibitor of refractory hypokalemia in a patient with Gitelman's syndrome.

@article{Mayan2002SuccessfulTB,
  title={Successful treatment by cyclooxyenase-2 inhibitor of refractory hypokalemia in a patient with Gitelman's syndrome.},
  author={Haim Mayan and Osnat Gurevitz and Zvi Farfel},
  journal={Clinical nephrology},
  year={2002},
  volume={58 1},
  pages={73-6}
}
Gitelman's syndrome is manifested by hypokalemic alkalosis, hypomagnesemia, hypocalciuria, normotensive hyperreninemia and hyperaldosteronism. Hypokalemia can at times be refractory to treatment. We present a patient refractory to a variety of drugs including indomethacin, the nonspecific COX inhibitor. Rofecoxib, a specific COX 2 inhibitor, promptly… CONTINUE READING