Successful sustained engraftment after reduced-intensity umbilical cord blood transplantation for adult patients with severe aplastic anemia.

@article{Yamamoto2011SuccessfulSE,
  title={Successful sustained engraftment after reduced-intensity umbilical cord blood transplantation for adult patients with severe aplastic anemia.},
  author={Hisashi Yamamoto and Daisuke Kato and Naoyuki Uchida and Kazuya Ishiwata and Hideki Araoka and Shinsuke Takagi and Nobuaki Nakano and Masanori Tsuji and Yuki Asano-Mori and Naofumi Matsuno and Kazuhiro Masuoka and Koji Izutsu and A Wake and Akiko Yoneyama and Shigeyoshi Makino and Shuichi Taniguchi},
  journal={Blood},
  year={2011},
  volume={117 11},
  pages={
          3240-2
        }
}
We retrospectively analyzed 12 consecutive adult severe aplastic anemia patients who received unrelated umbilical cord blood transplantation after a reduced-intensity conditioning regimen (RI-UCBT). The conditioning regimen consisted of 125 mg/m² fludarabine, 80 mg/m² melphalan, and 4 Gy of total body irradiation. The median infused total nucleated cell number and CD34(+) cell number were 2.50 × 10⁷/kg and 0.76 × 10⁵/kg, respectively. Eleven of the 12 patients achieved primary neutrophil and… CONTINUE READING

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