Successful single-dose teicoplanin prophylaxis against experimental streptococcal, enterococcal, and staphylococcal aortic valve endocarditis.

@article{Perdikaris1997SuccessfulST,
  title={Successful single-dose teicoplanin prophylaxis against experimental streptococcal, enterococcal, and staphylococcal aortic valve endocarditis.},
  author={G S Perdikaris and Angelos Pefanis and Helen Giamarellou and Apostolos N Nikolopoulos and Elias Margaris and Ismini A Donta and Artemis Tsitsika and Panayiotis Karayiannakos},
  journal={Antimicrobial agents and chemotherapy},
  year={1997},
  volume={41 9},
  pages={1916-21}
}
Teicoplanin is a glycopeptide antibiotic that is administered both intramuscularly and intravenously. It has a prolonged half-life and a less toxic profile in comparison to those of vancomycin. The efficacy of a single dose of teicoplanin (18 mg/kg of body weight given intramuscularly) for the prevention of endocarditis due to Streptococcus oralis… CONTINUE READING