Successful pregnancy after microsurgical transplantation of an intact ovary.

  title={Successful pregnancy after microsurgical transplantation of an intact ovary.},
  author={Sherman J. Silber and Gedis Grudzinskas and Roger G. Gosden},
  journal={The New England journal of medicine},
  volume={359 24},
This case demonstrates the potential for using whole-ovary transplantation between monozygotic twins who are discordant for premature ovarian failure, in order to restore fertility in the affected ... 
Whole Ovary Transplantation
Whole ovary cryopreservation with its' vascular pedicle with subsequent transplantation with a vascular anastomosis is one experimental approach to minimize the effects of ischemic damage including whole ovary transplantation.
Journal of Fertilization : In Vitro , IVF-Worldwide
Fertility preservation provides the pregnancy chances at the right time in patients or those who want to postpone childbearing for social or financial reasons. The majority of patients who can
Fertility Preservation in Girls
Pediatric hemato-oncology, reproductive endocrinology, surgery, anesthesia and bioethics perspectives are discussed and integrated to propose guidelines for offering ovarian cryopreservation to premenarcheal girls with cancer.
Children born after autotransplantation of cryopreserved ovarian tissue. A review of 13 live births
Ovarian cortex cryopreservation should be offered before gonadotoxic chemotherapy in all cases where there is a high risk of POF and where emergency IVF is not possible, according to a review of available options.
Transplantation of ovarian tissue.
The First Ovarian Tissue Transplant between Monozygotic Twin Sisters Discordant for Ovarian function in Latin America.
The first fresh ovarian tissue transplant between monozygotic twin sisters discordant for ovarian function, using the subcortical implant technique of ovarian tissue fragments, to take place in Latin America clearly highlights the potential of the technique as a therapeutic option for the preservation of fertility.
Ovary cryopreservation and transplantation for fertility preservation.
  • S. Silber
  • Biology, Medicine
    Molecular human reproduction
  • 2012
The aim of this review is to summarize the state-of-the-art of ovarian transplantation and cryopreservation. This field has progressed over the last half century from simple animal experiments to
Biennial review of infertility
The objective of this study was to establish a baseline for the selection of a woman suitable for IVF treatment with a history of previous miscarriages and to establish an experimental procedure.


Ovarian transplantation in a series of monozygotic twins discordant for ovarian failure.
Ten other pairs of monozygotic twins who were discordant for ovarian failure sought consultation at the center for ovarian transplantation, and a previously menopausal twin conceived spontaneously during the second menstrual cycle and delivered a healthy full-term baby.
Ovarian transplantation between monozygotic twins discordant for premature ovarian failure.
Threeozygotic 24-year-old twins presented with discordant ovarian function and one had had premature ovarian failure at the age of 14 years, whereas her sister had normal ovaries and three naturally conceived children received a transplant of ovarian cortical tissue from her sister by means of a minilaparotomy.
Ovarian tissue cryopreservation and transplantation: a review.
Advances in reproductive technology have made fertility preservation techniques a real possibility for patients whose gonadal function is threatened by premature menopause, or by treatments such as radiotherapy, chemotherapy or surgical castration, the review concludes.
Dynamics of follicular growth in the human: a model from preliminary results.
  • A. Gougeon
  • Biology, Medicine
    Human reproduction
  • 1986
The ovulatory follicle originates from a cohort of pre-antral follicles that have differentiated their theca interna 85 days earlier under the control of the high peri-ovulatory steroid and gonadotrophin levels.
Ovarian transplan1 . tation between monozygotic twins discordant for premature ovarian failure
  • N Engl J Med
  • 2005
Fertility after intact ovary transplantation
The successful transplantation in rats of ovaries, fallopian tubes and the upper segment of the uterus en bloc after storage in liquid nitrogen is described.
Ovarian transplan - 1 . tation between monozygotic twins discordant for premature ovarian failure