Successful outcome with day 4 embryo transfer after preimplantation diagnosis for genetically transmitted diseases.

@article{Grifo1998SuccessfulOW,
  title={Successful outcome with day 4 embryo transfer after preimplantation diagnosis for genetically transmitted diseases.},
  author={Jamie A. Grifo and K Giatras and Ya Xu Tang and Lewis C Krey},
  journal={Human reproduction},
  year={1998},
  volume={13 6},
  pages={1656-9}
}
Preimplantation genetic diagnosis was performed in 61 day 3 embryos obtained by in-vitro fertilization from seven patient carriers of haemophilia, Marfan's syndrome, Bloch-Sulzemberg syndrome (incontinentia pigmentosa) or X chromosome-linked immune deficiency, retinitis pigmentosa, and FG syndrome, which is characterized by mental retardation and hypotonia. After multiplex polymerase chain reaction, 16 embryos were diagnosed as being unaffected, and these were transferred to the uterus on the… CONTINUE READING
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