Successful oral doxycycline treatment of Lyme disease-associated facial palsy and meningitis.

@article{Dotevall1999SuccessfulOD,
  title={Successful oral doxycycline treatment of Lyme disease-associated facial palsy and meningitis.},
  author={Leif Dotevall and Lars Hagberg},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={1999},
  volume={28 3},
  pages={
          569-74
        }
}
  • L. DotevallL. Hagberg
  • Published 1 March 1999
  • Medicine
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Twenty-nine patients, aged 11-79 years (mean, 50 years), with Lyme neuroborreliosis, facial nerve palsy, and meningitis were treated with oral doxycycline (daily dose, 200-400 mg) for 9-17 days in a prospective, nonrandomized study. Facial paresis was bilateral in eight (28%) of the 29 patients. Twenty-six patients (90%) recovered without sequelae within 6 months, while three of the patients with bilateral facial palsy at admission had remaining paresis at follow-up. In five patients… 
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Outcome of facial palsy from Lyme disease in prospectively followed patients who had received corticosteroids.

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Oral doxycycline seems to be an effective, convenient and inexpensive alternative for the treatment of Lyme neuroborreliosis.

Follow-up of Patients Treated with Oral Doxycycline for Lyme neuroborreliosis

Oral doxycycline seems to be an effective, convenient and inexpensive alternative for the treatment of Lyme neuroborreliosis.

Adjunctive Corticosteroids for Lyme Neuroborreliosis Peripheral Facial Palsy - a prospective study with historical controls.

  • S. AvellanD. Bremell
  • Medicine
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
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Adjunctive corticosteroids neither improve nor impair the outcome for patients with Lyme neuroborreliosis peripheral facial palsy treated with doxycycline.

Intravenous ceftriaxone compared with oral doxycycline for the treatment of Lyme neuroborreliosis

Intravenous ceftriaxone or oral doxycycline was found to be effective, safe, and convenient for treatment of Lyme neuroborreliosis.

Oral antibiotic treatment and long-term outcomes of Lyme facial nerve palsy

For patients with Lyme facial nerve palsy in North America, treatment with oral doxycycline appears to be an effective therapeutic strategy.

A case of hemifacial paresis in a patient with Lyme neuroborreliosis treated with antibiotics in whom Borrelia meningitis developed.

It is a rare for meningitis to develop in a patient with cranial neuropathy who received doxycycline, and care should be exercised in the diagnosis of Lyme neuroborreliosis and evaluation of the response to treatment.

Successful treatment of neuroborreliosis with ten day regimens

The prognosis of neuroborreliosis in children 2 months after treatment seems to be excellent with 10-day treatment regimens, and facial paralysis persisted longer than other symptoms.

Lyme Neuroborreliosis Diagnosis and Treatment

Oral doxycycline can be considered an effective treatment for Lyme neuroborreliosis, irrespective of the severity of symptoms, and all patients with CNS symptoms improved on treatment with no need for retreatment.

SHOULD LYME DISEASE AFFECTING THE NERVOUS SYSTEM BE TREATED WITH ORAL OR INTRAVENOUS ANTIBIOTICS?

A 10-year-old girl presents complaining of headache and muscle aches and two days later she presents with right sided facial paralysis and worsening headache, and is commenced on a 3-week course of intravenous ceftriaxone.
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