Successful Treatment of Periungual Warts with Diluted Bleomycin Using Translesional Multipuncture Technique: A Pilot Prospective Study

@article{Alghamdi2011SuccessfulTO,
  title={Successful Treatment of Periungual Warts with Diluted Bleomycin Using Translesional Multipuncture Technique: A Pilot Prospective Study},
  author={Khalid M. Alghamdi and Huma Khurram},
  journal={Dermatologic Surgery},
  year={2011},
  volume={37},
  pages={486–492}
}
BACKGROUND The treatment of periungual warts is a therapeutic challenge. [] Key MethodRESULTS We recruited 15 patients with periungual warts from March 2007 to March 2008. Thirteen patients were male (86.6%); median age was 30. Seven patients (46.6%) demonstrated complete clearance 1 month after the first injection; two required two treatment sessions. Thirteen (86.6%) patients had complete clearance of the treated wart at the 6-month follow-up with only one injection. Wart recurrence was observed in two…

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References

SHOWING 1-10 OF 25 REFERENCES

Nail dystrophy following intralesional injections of bleomycin for a periungual wart.

A patient with a periungual wart lost his fingernail following intralesional bleomycin therapy, followed by regrowth of a dystrophic nail, which has persisted for two years following therapy.

Bleomycin in the treatment of recalcitrant warts.

An open label evaluation of the efficacy of imiquimod 5% cream in the treatment of recalcitrant subungual and periungual cutaneous warts

Topical imiquimod 5% cream is an interesting novel treatment for multiple periungual and subungual warts and its tolerability is excellent when compared to other commonly used modalities and there are few side effects.

Reduced dose of bleomycin in the treatment of recalcitrant warts.

The treatment of resistant warts with intralesional bleomycin: a controlled clinical trial

It was found that 87·5% of patients showed a more favourable response to bleomycin (P<0·001), and 76% of the fifty‐nine warts treated withBleomycin were cured by one to three injections of up to 0·2 ml of solution.

Warts of the Nail Unit: Surgical and Nonsurgical Approaches

  • A. TostiB. Piraccini
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2001
Definitive cure is not guaranteed by any therapy and periungual warts can recur and become larger after correct treatment, and keratolytic agents are the best first-line approach.

A new method of intralesional bleomycin therapy in the treatment of recalcitrant warts

It is concluded that tbis technique of intralesional bleomycin therapy is an effective, safe and generally well tolerated treatment for recalcitrant warts.

Outcome of carbon dioxide laser therapy for persistent cutaneous viral warts

The use of the CO2 laser may clear otherwise resistant viral warts but a significant morbidity may occur with this method of treatment.

Recalcitrant periungual verrucae: the role of carbon dioxide laser vaporization.

CARBON DIOXIDE LASER TREATMENT OF PERIUNGUAL AND SUBUNGUAL VIRAL WARTS

This is a restrospective study of the cure rates of forty patients with subungual and periungual viral warts treated with carbon dioxide laser vapourisation (total of 69 lesions). 70.6% (48/68)