Successful Treatment of Extensively Drug-Resistant Acinetobacter baumannii Peritoneal Dialysis Peritonitis with Intraperitoneal Polymyxin B and Ampicillin-Sulbactam

@article{Fitzpatrick2012SuccessfulTO,
  title={Successful Treatment of Extensively Drug-Resistant Acinetobacter baumannii Peritoneal Dialysis Peritonitis with Intraperitoneal Polymyxin B and Ampicillin-Sulbactam},
  author={Margaret A. Fitzpatrick and John S. Esterly and Michael J. Postelnick and Sarah H Sutton},
  journal={Annals of Pharmacotherapy},
  year={2012},
  volume={46},
  pages={e17 - e17}
}
OBJECTIVE: To describe a case of extensively drug-resistant (XDR) Acinetobacter baumannii peritoneal dialysis (PD)–associated peritonitis successfully treated with combination antibiotics, including intraperitoneal polymyxin B, with retention of the catheter. CASE SUMMARY: A 54-year-old woman with end-stage renal disease receiving chronic PD and recent antibiotic and hospital exposure presented with abdominal pain, nausea, and vomiting. She was found to have XDR A. baumannii PD peritonitis… 
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Newer antibiotics for the treatment of peritoneal dialysis-related peritonitis
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The potential use of newer antibiotics with activities against drug-resistant Gram-positive bacteria have been developed in the treatment of drug- resistant bacterial peritonitis in PD patients is discussed.
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The odds of catheter removal, hemodialysis transfer, and death were higher with Pseudomonas, other gram-negative, fungal, and polymicrobial peritonitis than with Acinetobacterperitonitis.
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The ISPD 2022 updated recommendations have revised and clarified definitions for refractory peritonitis, relapsing peritonritis, peritonopathy-associated catheter removal, PD-associated haemodialysis transfer, peritoneitis-associated death and peritonococcal dialysis-associated hospitalisation.
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Polymyxin B is another clinically available polymyxin that has re-emerged in clinical practice to treat infections caused by multi-drug (MDR) or extensively-drug-resistant (XDR) Gram-negative…
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Recommendations under the auspices of the International Society for Peritoneal Dialysis (ISPD) were first published in 1983 and revised in 1993, 1996, 2000, 2005, and 2010 are revised.
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This is the publisher's version, also available electronically from "http://journal.frontiersin.org".
Multiresistente gramnegative Erreger
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Eine Klassifizierung der Antibiotikaresistenz bei gramnegativen Bakterien eingef€uhrt, die sich an der Resistenz gegen klinische relevante Leitantibiotika orientiert, die bei schweren Infektionen eingesetzt werden.
Sürekli ayaktan periton diyalizi hastasında polimicrobiyal infektif endokarditi takiben gelişen karbapeneme dirençli, çoklu ilaca dirençli Acinetobacter baumannii’ye bağlı olarak gelişen peritonit
TLDR
Bu yazida, 60 yasinda kronik bobrek yetmezligi nedeniyle periton diyalizi uygulanan bir kadin hastada polimikrobiyal infektif endokarditi takiben A.baumannii’ ye bagli olarak gelisen ve mortal seyreden peritonit bildirilmis ve literatur gozden gecirilmistir.

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