Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.

@article{Brown1994SubunitsOT,
  title={Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.},
  author={J. D. Brown and B. Hann and K. F. Medzihradszky and M. Niwa and A. Burlingame and P. Walter},
  journal={The EMBO Journal},
  year={1994},
  volume={13}
}
  • J. D. Brown, B. Hann, +3 authors P. Walter
  • Published 1994
  • Biology, Medicine
  • The EMBO Journal
  • The signal recognition particle (SRP) is an evolutionarily conserved ribonucleoprotein (RNP) complex that functions in protein targeting to the endoplasmic reticulum (ER) membrane. Only two protein subunits of the SRP, Srp54p and Sec65p, and the RNA subunit, scR1, were previously known in the yeast Saccharomyces cerevisiae. Purification of yeast SRP by immunoaffinity chromatography revealed five additional proteins. Amino acid sequencing and cloning of the genes encoding four of these proteins… CONTINUE READING
    Signal sequences specify the targeting route to the endoplasmic reticulum membrane
    • 423
    • PDF

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 37 REFERENCES
    … genetics …
    • 4,413
    • PDF
    Fractions around the 16S marker were diluted 1:1 with immunoprecipitation buffer [IPB; 50 mM Tris-HCI pH 7
    • 1991
    Methods Enzymol
    • 1991
    Methods in Yeast Genetics
    • 2,668
    • Highly Influential
    Proc. Natl Acad. Sci. USA
    • 1988
    Trends Biochem. Sci
    • 1988
    Am. Soc. Mass Spectrom
    • 1994
    Anal. Biochem
    • 1992
    Annu. Rev. Cell Biol
    • 1986
    Atlas ofProtein Sequence and Structure. National Biomedical Research Foundation
    • 1972