Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene.

@article{Jongh1990SubunitsOP,
  title={Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene.},
  author={K S de Jongh and Carol Warner and William A. Catterall},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 25},
  pages={14738-41}
}
Polyacrylamide gel electrophoresis of purified rabbit skeletal muscle L-type calcium channel before and after reduction of disulfide bonds confirmed that 27- and 24-kDa forms of the delta subunit are disulfide-linked to the 143-kDa alpha 2 subunit. The amino acid sequences of three peptides obtained by tryptic digestion of the delta subunits corresponded to amino acid sequences predicted from the 3' region of the mRNA encoding alpha 2. One of these peptides had the same sequence as the N… CONTINUE READING

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