Subunit-specific P2X-receptor expression defines chemosensory properties of trigeminal neurons.

@article{Spehr2004SubunitspecificPE,
  title={Subunit-specific P2X-receptor expression defines chemosensory properties of trigeminal neurons.},
  author={Jennifer Spehr and Marc Spehr and Hanns Hatt and Christian H Wetzel},
  journal={The European journal of neuroscience},
  year={2004},
  volume={19 9},
  pages={2497-510}
}
The facial innervation pattern of trigeminal nerve fibres comprises the innervation of the nasal epithelium, where free trigeminal nerve endings contribute to detection and discrimination of chemical stimuli including odourants. The signal transduction mechanisms in sensory nerve endings underlying perception of chemical stimuli remain widely uncovered. Here, we characterized trigeminal ATP-activated P2X receptors in cultured rat trigeminal neurons and investigated their role in chemoperception… CONTINUE READING

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