Subunit Composition and Structure of GABAA-Receptor Subtypes

@inproceedings{Sieghart2007SubunitCA,
  title={Subunit Composition and Structure of GABAA-Receptor Subtypes},
  author={Werner Sieghart},
  year={2007}
}
γ-Aminobutyric acid (GABAA) receptors are the major inhibitory neurotransmitter receptors in the brain and are the site of action of many clinically important drugs. They are made up of five subunits that can belong to eight different subunit classes. Depending on their subunit composition these receptors exhibit distinct pharmacological and electrophysiological properties. The distinct but overlapping regional and cellular distribution of these subunits gives rise to the formation of a large… CONTINUE READING