Subtypes of physical frailty: Latent class analysis and associations with clinical characteristics and outcomes

@article{Liu2017SubtypesOP,
  title={Subtypes of physical frailty: Latent class analysis and associations with clinical characteristics and outcomes},
  author={Li-Kuo Liu and Chao-Yu Guo and Wei‐Ju Lee and LiangYu Chen and An-Chun Hwang and Ming-Hsien Lin and Li-Ning Peng and Liang‐Kung Chen and K Y Liang},
  journal={Scientific Reports},
  year={2017},
  volume={7}
}
Frailty is a well-recognized geriatric syndrome with various definitions and conceptual frameworks. This study aimed to use latent class analysis to discover potential subtypes of pre-frail and frail older people. Data from the I-Lan Longitudinal Aging Study (ILAS), a community-based cohort study was used for analysis. Latent class analysis was applied to characterize classes or subgroups with different frailty phenotypes among ILAS participants targeting older adults aged 65 and above, capable… 
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47 Citations
Highly Influential Citations
3
Background Citations
12
Methods Citations
5
Results Citations
7

47 Citations

Frailty Status Typologies in Spanish Older Population: Associations with Successful Aging
TLDR
Four different patterns of frailty attributes were revealed and further offered evidence on individuals’ differential status of health regarding distinct frailty conditions as compared to other frailty subgroups.
The frail older person does not exist: development of frailty profiles with latent class analysis
TLDR
The research provides an empirical base for meaningful frailty profiles based on the physical, psychological, social and cognitive domains of functioning and the severity of the problems within these domains.
Different Cognitive Frailty Models and Health- and Cognitive-related Outcomes in Older Age: From Epidemiology to Prevention
TLDR
The framework for the definition, different models, and the current epidemiology of Cognitive frailty are reviewed, also describing neurobiological mechanisms, and exploring the possible prevention of the cognitive frailty progression are reviewed.
Physical frailty and cognitive impairment in older nursing home residents: a latent class analysis
TLDR
Findings indicate the heterogeneous presentations of physical frailty in older nursing home residents and additional evidence on the interrelationship betweenPhysical frailty and cognitive impairment.
Heterogeneous Influence of Frailty Phenotypes in Age-Related Hearing Loss and Tinnitus in Chinese Older Adults: An Explorative Study
TLDR
Frailty phenotypes have divergent association with hearing loss (HL) and tinnitus, and patients with physical frailty (mobility frailty) or who are robust were found to have lower probability of developing severe HL andTinnitus than those with only cognitive decline, or CF.
Identification of five frailty profiles in community-dwelling individuals aged 50-75: A latent class analysis of the SUCCEED survey data.
Cognitive frailty predicting all-cause mortality among community-living older adults in Taiwan: A 4-year nationwide population-based cohort study
TLDR
Dynapenia and cognitive impairment synergistically contribute to the mortality risk for the participants in this study and further study is needed to explore the underlying pathophysiology and the reversibility of CF.
Development of frailty subtypes and their associated risk factors among the community-dwelling elderly population
TLDR
The findings confirm the heterogeneity of frailty and suggest that different frail elderly individuals need more targeted care interventions.
Role of sarcopenia in the frailty transitions in older adults: a population-based cohort study.
TLDR
Transitions within frailty status, but not the risk of death associated to frailty, are modulated by the presence of sarcopenia.
Portals to frailty? Data-driven analyses detect early frailty profiles
TLDR
A data-driven approach to early frailty assessment detected differentiable profiles that may be characterized as morbidity-intensive portals into broader and chronic frailty.
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