Subtype distribution and long-term titer fluctuation patterns of serum anti-Epstein–Barr virus antibodies in a non-nasopharyngeal carcinoma population from an endemic area in South China: a cohort study

@inproceedings{Du2016SubtypeDA,
  title={Subtype distribution and long-term titer fluctuation patterns of serum anti-Epstein–Barr virus antibodies in a non-nasopharyngeal carcinoma population from an endemic area in South China: a cohort study},
  author={Jin-lin Du and Sui-Hong Chen and Qi-Hong Huang and Shang-Hang Xie and Yan-Fang Ye and Rui Gao and Jie Guo and Mengjie Yang and Qing Liu and Ming-huang Hong and Su-mei Cao},
  booktitle={Chinese journal of cancer},
  year={2016}
}
BACKGROUND Serum immunoglobulin A antibodies against Epstein-Barr virus (EBV), viral capsid antigen (VCA-IgA) and early antigen (EA-IgA), are used to screen for nasopharyngeal carcinoma (NPC) in endemic areas. However, their routine use has been questioned because of a lack of specificity. This study aimed to determine the distributions of different subtypes of antibody and to illustrate how the natural variation patterns affect the specificity of screening in non-NPC participants. METHODS… CONTINUE READING

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