Subthalamic neurons coordinate basal ganglia function through differential neural pathways.

@article{Yasoshima2005SubthalamicNC,
  title={Subthalamic neurons coordinate basal ganglia function through differential neural pathways.},
  author={Yasunobu Yasoshima and Nobuyuki Kai and Shigetaka Yoshida and Sadao Shiosaka and Yoshimasa Koyama and Yukihiko Kayama and Kazuto Kobayashi},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2005},
  volume={25 34},
  pages={7743-53}
}
The subthalamic nucleus (STN) is a key component of basal ganglia circuitry that mediates a variety of motor functions. The STN neurons send glutamatergic projections to the output structures of basal ganglia, including the substantia nigra pars reticulata (SNr) and the entopeduncular nucleus, and also innervate the globus pallidus (GP). However, the mechanism by which the STN regulates motor functions in the neural circuitry is not fully understood. Here we performed conditional ablation of… CONTINUE READING

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