Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial.

@article{Okun2012SubthalamicDB,
  title={Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial.},
  author={Michael S. Okun and Bruno V Gallo and George T Mandybur and Jonathan Russell Jagid and Kelly Foote and Fredy J. Revilla and Ron Alterman and Joseph Jankovic and Richard Simpson and Fred Junn and Leo Verhagen and Jeff Arle and Blair Ford and R. A. Romero N. A. Goodman and R. Malcolm Stewart and Stacy Horn and Gordon Baltuch and Brian H. Kopell and Frederick Marshall and Delea Peichel and Rajesh Pahwa and Kelly E. Lyons and Alexander I Tr{\"o}ster and Jerrold L. Vitek and Michele Tagliati},
  journal={The Lancet. Neurology},
  year={2012},
  volume={11 2},
  pages={140-9}
}
BACKGROUND The effects of constant-current deep brain stimulation (DBS) have not been studied in controlled trials in patients with Parkinson's disease. We aimed to assess the safety and efficacy of bilateral constant-current DBS of the subthalamic nucleus. METHODS This prospective, randomised, multicentre controlled trial was done between Sept 26, 2005, and Aug 13, 2010, at 15 clinical sites specialising in movement disorders in the USA. Patients were eligible if they were aged 18-80 years… CONTINUE READING
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