Subthalamic DBS replaces levodopa in Parkinson's disease: two-year follow-up.

Abstract

BACKGROUND Subthalamic nucleus (STN) deep brain stimulation (DBS) of patients with PD allows reduction of antiparkinsonian medication but has only a mild direct effect on dyskinesia. Since antiparkinsonian medication has short- and long-term effects that may prevent an estimate of the maximal possible impact of STN DBS, such medication was used at the… (More)

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